(1H-indol-4-yl)methanamine → HCID 24990476, compound

HRID 1170170Notes

Reaction equation

HRID 1170170 reaction equation
I[C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][C:6](Cl)=[N:7]2.[O:13]1[C:18]2[CH:19]=[CH:20][CH:21]=[C:22]([CH2:23][NH2:24])[C:17]=2[O:16][CH2:15][CH2:14]1.[NH2:25][CH2:26][C:27]1[CH:35]=[CH:34][CH:33]=[C:32]2[C:28]=1[CH:29]=[CH:30][NH:31]2>>[O:13]1[C:18]2[CH:19]=[CH:20][CH:21]=[C:22]([CH2:23][NH:24][C:6]3[CH:5]=[CH:4][C:3]4[C:2]([NH:25][CH2:26][C:27]5[CH:35]=[CH:34][CH:33]=[C:32]6[C:28]=5[CH:29]=[CH:30][NH:31]6)=[CH:11][CH:10]=[CH:9][C:8]=4[N:7]=3)[C:17]=2[O:16][CH2:15][CH2:14]1

Participants

4

Reactant 3

HCID 280302(1H-indol-4-yl)methanamineHCID 2795040HCID 2795040, compoundHCID 457894242-Chloro-5-iodoquinoline

Product 1

HCID 24990476HCID 24990476, compound

Procedure

The title compound, MS: m/e=437.4 (M+H+), was prepared in accordance with the general method of example 1 from 5-iodo-2-chloroquinoline, 2,3-dihydro-1,4-benzodioxin-5-ylmethylamine and 4-aminomethylindole.

Sources & evidence

ORD record
ord-d27691dfc2ae4e538a987d8903617468
Source dataset
uspto-grants-2010_11
Patent number
US07825253B2

Reaction notes

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