4-Aminoindan → HCID 24990827, compound

HRID 1170175Notes

Reaction equation

HRID 1170175 reaction equation
[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][C:8](Cl)=[N:9]2)([O-])=O.[F:15][C:16]1[CH:17]=[C:18]([S:23](Cl)(=[O:25])=[O:24])[CH:19]=[C:20]([F:22])[CH:21]=1.[NH2:27][C:28]1[CH:36]=[CH:35][CH:34]=[C:33]2[C:29]=1[CH2:30][CH2:31][CH2:32]2>>[F:15][C:16]1[CH:17]=[C:18]([S:23]([NH:1][C:4]2[CH:13]=[CH:12][CH:11]=[C:10]3[C:5]=2[CH:6]=[CH:7][C:8]([NH:27][C:28]2[CH:36]=[CH:35][CH:34]=[C:33]4[C:29]=2[CH2:30][CH2:31][CH2:32]4)=[N:9]3)(=[O:25])=[O:24])[CH:19]=[C:20]([F:22])[CH:21]=1

Participants

4

Reactant 3

HCID 1225694-AminoindanHCID 3192512-Chloro-5-nitroquinolineHCID 27740583,5-Difluorobenzenesulfonyl chloride

Product 1

HCID 24990827HCID 24990827, compound

Procedure

The title compound, MS: m/e=452.0 (M+H+), was prepared in accordance with the general method of example 89 from 5-nitro-2-chloroquinoline, 3,5-difluorobenzenesulfonylchloride and 4-aminoindane.

Sources & evidence

ORD record
ord-f8b3e05eafdd4bd2b7cbf1d4d74151f4
Source dataset
uspto-grants-2010_11
Patent number
US07825253B2

Reaction notes

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