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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1170182Generated: October 26, 2026

4-Fluorobenzenesulfonyl chloride → 4-Fluoro-N-[2-(2-methyl-benzofuran-7-ylamino)-quinolin-5-yl]-benzenesulfonamide

https://huagongshe.com/reaction/1170182

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluorobenzenesulfonyl chlorideHCID 9588—
Reactant2-Chloro-5-nitroquinolineHCID 319251—
Reactant2-Methyl-benzofuran-7-ylamineHCID 3157485—
Product4-Fluoro-N-[2-(2-methyl-benzofuran-7-ylamino)-quinolin-5-yl]-benzenesulfonamideHCID 24991200—

Reaction Steps

The title compound, MS: m/e=448.0 (M+H+), was prepared in accordance with the general method of example 58 from 5-nitro-2-chloroquinoline, (2-methyl-1-benzofuran-7-yl)amine and 4-fluorobenzenesulfonylchloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07825253B2
Source datasetuspto-grants-2010_11
ORD IDord-13521e2796444cbe9a600f1e3543a530
Source noteuspto-grants-2010_11