HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-5-nitroquinoline → Rac-3,5-difluoro-n-[2-(2-methyl-2,3-dihydro-benzofuran-7-ylamino)-quinolin-5-yl]-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-5-nitroquinoline | HCID 319251 | — |
| Reactant | 3,5-Difluorobenzenesulfonyl chloride | HCID 2774058 | — |
| Reactant | HCID 13535826 | HCID 13535826 | — |
| Product | Rac-3,5-difluoro-n-[2-(2-methyl-2,3-dihydro-benzofuran-7-ylamino)-quinolin-5-yl]-benzenesulfonamide | HCID 24991558 | — |
Reaction Steps
The title compound, MS: m/e=468.3 (M+H+), was prepared in accordance with the general method of example 89 from 5-nitro-2-chloroquinoline, 3,5-difluorobenzenesulfonylchloride and 2,3-dihydro-2-methyl-7-benzofuranamine (CAS 26210-74-2).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07825253B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-e251b91f210b4ee1a84288291de36fe4 |
| Source note | uspto-grants-2010_11 |