Thiochroman-4-one → HCID 24991559, compound

HRID 1170187Notes

Reaction equation

HRID 1170187 reaction equation
[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][C:8](Cl)=[N:9]2)([O-])=O.[CH3:15][C:16]1[O:20][C:19]([CH2:21][NH2:22])=[CH:18][CH:17]=1.[S:23]1[C:32]2[C:27](=[CH:28][CH:29]=[CH:30][CH:31]=2)[C:26](=O)[CH2:25][CH2:24]1>>[CH3:15][C:16]1[O:20][C:19]([CH2:21][NH:22][C:8]2[CH:7]=[CH:6][C:5]3[C:4]([NH:1][CH:26]4[C:27]5[C:32](=[CH:31][CH:30]=[CH:29][CH:28]=5)[S:23][CH2:24][CH2:25]4)=[CH:13][CH:12]=[CH:11][C:10]=3[N:9]=2)=[CH:18][CH:17]=1

Participants

4

Reactant 3

HCID 19048Thiochroman-4-oneHCID 3192512-Chloro-5-nitroquinolineHCID 27246835-Methyl-2-furylmethylamine

Product 1

HCID 24991559HCID 24991559, compound

Procedure

The title compound, MS: m/e=402.5 (M+H+), was prepared from 5-nitro-2-chloroquinoline, 5-methyl-2-furanmethanamine and thiochroman-4-one as described in example 26.

Sources & evidence

ORD record
ord-7baeebd5724a43f08a363aeb9a5965aa
Source dataset
uspto-grants-2010_11
Patent number
US07825253B2

Reaction notes

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