HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-5-nitroquinoline → N-[2-(2,3-Dihydro-benzofuran-7-ylamino)-quinolin-5-yl]-3,5-difluoro-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-5-nitroquinoline | HCID 319251 | — |
| Reactant | 3,5-Difluorobenzenesulfonyl chloride | HCID 2774058 | — |
| Reactant | 2,3-Dihydro-1-benzofuran-7-amine | HCID 12805950 | — |
| Product | N-[2-(2,3-Dihydro-benzofuran-7-ylamino)-quinolin-5-yl]-3,5-difluoro-benzenesulfonamide | HCID 24991899 | — |
Reaction Steps
The title compound, MS: m/e=454.3 (M+H+), was prepared in accordance with the general method of example 89 from 5-nitro-2-chloroquinoline, 3,5-difluorobenzenesulfonylchloride and 7-amino-2,3-dihydrobenzofuran (CAS 13414-56-7).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07825253B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-5b6b8d7c7d5f4840991f675b3cbdd9fc |
| Source note | uspto-grants-2010_11 |