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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1170193Generated: October 31, 2026

2-Chloro-5-nitroquinoline → N5-(1H-Indol-4-ylmethyl)-N2-(2-methyl-2,3-dihydro-benzofuran-7-yl)-quinoline-2,5-diamine

https://huagongshe.com/reaction/1170193

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-5-nitroquinolineHCID 319251—
ReactantIndole-4-carboxaldehydeHCID 333703—
ReactantHCID 13535826HCID 13535826—
ProductN5-(1H-Indol-4-ylmethyl)-N2-(2-methyl-2,3-dihydro-benzofuran-7-yl)-quinoline-2,5-diamineHCID 24991900—

Reaction Steps

The title compound, MS: m/e=421.4 (M+H+), was prepared from 5-nitro-2-chloroquinoline, 2,3-dihydro-2-methyl-7-benzofuranamine (CAS 26210-74-2) and indole-4-carbaldehyde as described in example 26.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07825253B2
Source datasetuspto-grants-2010_11
ORD IDord-b8a26f4e12ea47c59c7c2ca0083cc01f
Source noteuspto-grants-2010_11