5-Methyl-2-furylmethylamine → HCID 24991902, compound

HRID 1170195Notes

Reaction equation

HRID 1170195 reaction equation
I[C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][C:6](Cl)=[N:7]2.[CH3:13][C:14]1[O:18][C:17]([CH2:19][NH2:20])=[CH:16][CH:15]=1.[O:21]1[C:30]2[C:25](=[CH:26][CH:27]=[CH:28][CH:29]=2)[CH:24]([NH2:31])[CH2:23][CH2:22]1>>[O:21]1[C:30]2[C:25](=[CH:26][CH:27]=[CH:28][CH:29]=2)[CH:24]([NH:31][C:2]2[C:3]3[CH:4]=[CH:5][C:6]([NH:20][CH2:19][C:17]4[O:18][C:14]([CH3:13])=[CH:15][CH:16]=4)=[N:7][C:8]=3[CH:9]=[CH:10][CH:11]=2)[CH2:23][CH2:22]1

Participants

4

Reactant 3

HCID 27246835-Methyl-2-furylmethylamineHCID 49619573,4-Dihydro-2H-1-benzopyran-4-amineHCID 457894242-Chloro-5-iodoquinoline

Product 1

HCID 24991902HCID 24991902, compound

Procedure

The title compound, MS: m/e=386.3 (M+H+), was prepared in accordance with the general method of example 1 from 5-iodo-2-chloroquinoline, 5-methyl-2-furanmethanamine and 3,4-dihydro-2H-chromen-4-ylamine.

Sources & evidence

ORD record
ord-d42c13fb2afc4f79ad376f8160f62abe
Source dataset
uspto-grants-2010_11
Patent number
US07825253B2

Reaction notes

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