3-tert-Butylaniline → HCID 24986783, compound

HRID 1170209Notes

Reaction equation

HRID 1170209 reaction equation
[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][C:8](Cl)=[N:9]2)([O-])=O.[F:15][C:16]1[CH:17]=[C:18]([S:23](Cl)(=[O:25])=[O:24])[CH:19]=[C:20]([F:22])[CH:21]=1.[C:27]([C:31]1[CH:32]=[C:33]([CH:35]=[CH:36][CH:37]=1)[NH2:34])([CH3:30])([CH3:29])[CH3:28]>>[C:27]([C:31]1[CH:32]=[C:33]([NH:34][C:8]2[CH:7]=[CH:6][C:5]3[C:10](=[CH:11][CH:12]=[CH:13][C:4]=3[NH:1][S:23]([C:18]3[CH:17]=[C:16]([F:15])[CH:21]=[C:20]([F:22])[CH:19]=3)(=[O:25])=[O:24])[N:9]=2)[CH:35]=[CH:36][CH:37]=1)([CH3:30])([CH3:28])[CH3:29]

Participants

4

Reactant 3

HCID 793343-tert-ButylanilineHCID 3192512-Chloro-5-nitroquinolineHCID 27740583,5-Difluorobenzenesulfonyl chloride

Product 1

HCID 24986783HCID 24986783, compound

Procedure

The title compound, MS: m/e=468.3 (M+H+), was prepared in accordance with the general method of example 89 from 5-nitro-2-chloroquinoline, 3,5-difluorobenzenesulfonylchloride and 3-tert.butyl-aniline.

Sources & evidence

ORD record
ord-345229f5c8124a329a05b14967ca9fbc
Source dataset
uspto-grants-2010_11
Patent number
US07825253B2

Reaction notes

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