2,2-Dimethyl-2,3-dihydro-1-benzofuran-7-amine → HCID 24986784, compound

HRID 1170210Notes

Reaction equation

HRID 1170210 reaction equation
I[C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][C:6](Cl)=[N:7]2.[NH2:13][C:14]1[C:22]2[O:21][C:20]([CH3:24])([CH3:23])[CH2:19][C:18]=2[CH:17]=[CH:16][CH:15]=1.[N:25]1[CH:30]=[CH:29][CH:28]=[C:27]([CH:31]([NH2:33])[CH3:32])[CH:26]=1>>[CH3:23][C:20]1([CH3:24])[CH2:19][C:18]2[CH:17]=[CH:16][CH:15]=[C:14]([NH:13][C:6]3[CH:5]=[CH:4][C:3]4[C:2]([NH:33][CH:31]([C:27]5[CH:26]=[N:25][CH:30]=[CH:29][CH:28]=5)[CH3:32])=[CH:11][CH:10]=[CH:9][C:8]=4[N:7]=3)[C:22]=2[O:21]1

Participants

4

Reactant 3

HCID 916972,2-Dimethyl-2,3-dihydro-1-benzofuran-7-amineHCID 27716881-(Pyridin-3-yl)ethan-1-amineHCID 457894242-Chloro-5-iodoquinoline

Product 1

HCID 24986784HCID 24986784, compound

Procedure

The title compound, MS: m/e=411.5 (M+H+), was prepared in accordance with the general method of example 1 from 5-iodo-2-chloroquinoline, 7-amino-2,3-dihydro-2,2-dimethylbenzofuran (CAS 68298-46-4) and rac-1-pyridine-3-yl-ethylamine.

Sources & evidence

ORD record
ord-eb79732838fd490882045b8887ee2ec2
Source dataset
uspto-grants-2010_11
Patent number
US07825253B2

Reaction notes

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