2-Chloro-5-nitroquinoline → HCID 178420609, compound

HRID 1170213Notes

Reaction equation

HRID 1170213 reaction equation
[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][C:8](Cl)=[N:9]2)([O-])=O.[CH:15]1([C:18]2[CH:19]=[C:20]([CH:22]=[CH:23][CH:24]=2)[NH2:21])[CH2:17][CH2:16]1.[NH:25]1[C:29]2[CH:30]=[CH:31][C:32]([CH:34]=O)=[CH:33][C:28]=2[N:27]=[CH:26]1>>[NH:25]1[C:29]2[CH:30]=[CH:31][C:32]([CH2:34][NH:1][C:4]3[C:5]4[CH:6]=[CH:7][C:8]([NH:21][C:20]5[CH:22]=[CH:23][CH:24]=[C:18]([CH:15]6[CH2:17][CH2:16]6)[CH:19]=5)=[N:9][C:10]=4[CH:11]=[CH:12][CH:13]=3)=[CH:33][C:28]=2[N:27]=[CH:26]1

Participants

4

Reactant 3

HCID 3192512-Chloro-5-nitroquinolineHCID 120321393-CyclopropylanilineHCID 178418743HCID 178418743, compound

Product 1

HCID 178420609HCID 178420609, compound

Procedure

The title compound, MS: m/e=406.5 (M+H+), was prepared from 5-nitro-2-chloroquinoline, 3-cyclopropylaniline and 1H-benzimidazole-5-carbaldehyde as described in example 26.

Sources & evidence

ORD record
ord-8bbafa65df6e4ec0a9cfeb6a3e91149e
Source dataset
uspto-grants-2010_11
Patent number
US07825253B2

Reaction notes

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