2-Chloro-5-nitroquinoline → HCID 178433273, compound

HRID 1170214Notes

Reaction equation

HRID 1170214 reaction equation
[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][C:8](Cl)=[N:9]2)([O-])=O.[CH:15]1([C:18]2[CH:19]=[C:20]([CH:22]=[CH:23][CH:24]=2)[NH2:21])[CH2:17][CH2:16]1.[CH3:25][C:26]1[N:27]=[CH:28][NH:29][C:30]=1[CH:31]=O>>[CH:15]1([C:18]2[CH:19]=[C:20]([NH:21][C:8]3[CH:7]=[CH:6][C:5]4[C:4]([NH:1][CH2:25][C:26]5[NH:27][CH:28]=[N:29][C:30]=5[CH3:31])=[CH:13][CH:12]=[CH:11][C:10]=4[N:9]=3)[CH:22]=[CH:23][CH:24]=2)[CH2:17][CH2:16]1

Participants

4

Reactant 3

HCID 3192512-Chloro-5-nitroquinolineHCID 27958875-Methyl-1H-imidazole-4-carbaldehydeHCID 120321393-Cyclopropylaniline

Product 1

HCID 178433273HCID 178433273, compound

Procedure

The title compound, MS: m/e=370.4 (M+H+), was prepared from 5-nitro-2-chloroquinoline, 3-cyclopropylaniline and 4-methyl-1H-imidazole-5-carbaldehyde as described in example 26.

Sources & evidence

ORD record
ord-e294895db7b84a58a914d4b09fcd7a55
Source dataset
uspto-grants-2010_11
Patent number
US07825253B2

Reaction notes

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