Methanol → 4-(2-Quinolin-2-yl-ethyl)-benzoic acid

Beteiligte Stoffe

Reaktionsschritte

To a solution of 4-(2-Quinolin-2-yl-ethyl)-benzoic acid methyl ester (680 mg) in THF (11 ml)/methanol (3 ml) was added 1N sodium hydroxide solution (4.67 ml). The reaction mixture stirred for 4 h. and the pH adjusted to 3. The white solid was filtered to provide the title compound (550 mg, 86%). MS: (M+H m/z=278.1).

Herkunft & Nachweise