HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-{4-[4-Pyridin-4-YL-1-(2,2,2-trifluoro-ethyl)-1H-pyrazol-3-YL]-phenoxymethyl}-quinoline → 4-[3-(4-Benzyloxy-2-fluoro-phenyl)-1-(2,2,2-trifluoroethyl)-1H-pyrazol-4-yl]-pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-{4-[4-Pyridin-4-YL-1-(2,2,2-trifluoro-ethyl)-1H-pyrazol-3-YL]-phenoxymethyl}-quinoline | HCID 11648276 | — |
| Reactant | HCID 178505957 | HCID 178505957 | — |
| Product | 4-[3-(4-Benzyloxy-2-fluoro-phenyl)-1-(2,2,2-trifluoroethyl)-1H-pyrazol-4-yl]-pyridine | HCID 68575305 | — |
Reaction Steps
Following the procedure for the preparation of 2-{4-[-Pyridin-4-yl-1-(2,2,2-trifluoroethyl)-1H-pyrazol-3-yl]-phenoxymethyl}-quinoline but substituting 4-[3-(4-Benzyloxy-2-fluoro-phenyl)-1H-pyrazol-4-yl]-pyridine provided the title compound. MS: (M+H m/z=428.4).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07825254B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-aaeaa88a3f124744b57689f5ae3b0938 |
| Source note | uspto-grants-2010_11 |