HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chlorobenzoyl chloride → Ethyl 2-(2-chlorobenzoyl)-3-dimethylaminopropenoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chlorobenzoyl chloride | HCID 69110 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | Ethyl 3,3-dimethylaminoacrylate | HCID 85819813 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | Ethyl 2-(2-chlorobenzoyl)-3-dimethylaminopropenoate | HCID 54509863 | — |
Reaction Steps
A mixture of ethyl 3,3-dimethylaminoacrylate (4.68 g, 32.7 mmol) and N,N-diisopropylethylamine (12 mL, 8.9 g, 69 mmol) was stirred at rt and a solution of 2-chlorobenzoyl chloride (5.72 g, 32.7 mmol) in 30 mL of toluene was added over 5 mins.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07825278B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-48fe0e069c824971aa6c0af41ecb916f |
| Source note | uspto-grants-2010_11 |