Benzyl-5-(N-FMOC-L-valyloxy)-4-stearoyloxy-2-pentenoate → 5-(N-FMOC-L-valyloxy)-4-stearoyloxy-pentanoic Acid

Participants

Reaction Steps

A solution of benzyl 5-(N-FMOC-L-valyloxy)-4-stearoyloxy-2-pentenoate (3.8 g, 4.69 mmole) in 50 ml ethyl acetate was hydrogenated with 10% palladium on charcoal (0.5 g) at normal pressure for five hours at room temperature. The catalyst was filtered and washed with ethyl acetate and 1,4-dioxane. The solution was evaporated under reduced pressure Yield: 3.3 g=99%

Provenance & Evidence