HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chlorophenylacetic acid → HCID 67373683, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chlorophenylacetic acid | HCID 15879 | — |
| Reactant | Cyclohexanecarboxaldehyde | HCID 16275 | — |
| Reactant | Cyclohexyl isocyanide | HCID 79129 | — |
| Reactant | Methoxyphenylacetic acid | HCID 107202 | — |
| Reactant | Cyclopentyl Isocyanide | HCID 2734784 | — |
| Reactant | (Tetrahydro-thiopyran-4-YL)-acetaldehyde | HCID 23532962 | — |
| Reactant | 2-(2-Benzyl-6-chloro-5-fluoro-benzoimidazol-1-yl)-2,N-dicyclohexyl-acetamide | HCID 67373623 | — |
| Product | HCID 67373683 | HCID 67373683 | — |
Reaction Steps
The title compound was prepared in analogy to Example 1, replacing (2-amino-4,5-difluoro-phenyl)-carbamic acid tert-butyl ester with (2-amino-4-chloro-5-fluoro-phenyl)-carbamic acid tert-butyl ester (([CAS RN 579474-50-3]), Example 47), cyclohexanecarbaldehyde with tetrahydro-2H-thiopyran-4-acetaldehyde ([CAS RN 372159-78-9]), (3-chloro-phenyl)-acetic acid with DL-α-methoxyphenylacetic acid ([CAS RN 7021-09-2]) and cyclohexyl isocyanide with cyclopentyl isocyanide ([CAS RN 68498-54-4]). MS (ISP): 530.3 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07825258B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-9731c61a61f34febb5d5215459b09f28 |
| Source note | uspto-grants-2010_11 |