Hydrochloric Acid → HCID 16732350, compound

Participants

Reaction Conditions

Reaction Steps

Into 200 ml of dehydrated THF, tetrahydrofuran, 20 g of 7-bromobenzanthracene obtained above was dissolved, and the obtained solution was cooled at −62° C. To the cooled solution, 50 ml of a 1.6 M hexane solution of normal-butyllithium was added dropwise, and the resultant mixture was stirred for 30 minutes. The temperature was raised to −5° C. and then lowered to −64° C. To the cooled fluid, a THF solution of 22.4 g of trimethyl borate was added dropwise. After one night, the reaction fluid was adjusted at the acidic condition with a dilute hydrochloric acid, treated by extraction with toluene and washed with water and a saturated aqueous solution of sodium chloride, and the organic layer was dried with anhydrous sodium sulfate. After the solvent was removed by distillation, the obtained residue was crystallized from toluene/hexane, and 14 g of 7-benzanthraceneboronic acid was obtained as cream crystals (the yield: 79%).

Provenance & Evidence