反应详情

9-Methoxy-6-(piperazin-1-yl)-11H-indeno[1,2-c]quinolin-11-one O-2-(dimethylamino)ethyl oxime (6r) was prepared substantially according to the procedures as set forth in the above Synthesis Example 18, except that compound 6p and 2-dimethylaminoethyl chloride·HCl were used in place of compound 5x and epichlorohydrin, respectively, giving the title compound at a yield of 45%.

1. custom9-Methoxy-6-(piperazin-1-yl)-11H-indeno[1,2-c]quinolin-11-one O-2-(dimethylamino)ethyl oxime (6r) was prepared substantially