HuagongsheHuagongshe Chemistry Print Report · For research reference only
Carbon tetrabromide → 2-(4-Fluoro-benzyl)-benzofuran-5-carbaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Carbon tetrabromide | HCID 11205 | — |
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | HCID 68718678 | HCID 68718678 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2-(4-Fluoro-benzyl)-benzofuran-5-carbaldehyde | HCID 57608254 | — |
Reaction Steps
Into a methylene chloride (4 mL) solution of 5-[1,3]dioxolan-2-yl-2-(4-fluoro-benzyl)-benzofuran (100 mg, 0.335 mmol) and carbon tetrabromide (222 mg, 0.67 mmol) was dropped a methylene chloride (1 mL) solution of triphenylphosphine (176 mg, 0.67 mmol), while cooling with ice.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07829585B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-733b73e6e0bf423a9764411af17f67c7 |
| Source note | uspto-grants-2010_11 |