Phthalimide → HCID 57608224, compound

Participants

Reaction Steps

To a tetrahydrofuran (5 mL) solution of (2-(4-fluoro-benzyl)-benzofuran-5-yl)-methanol (83 mg, 0.324 mmol) described in Production Example 76-1-2 were added triphenylphosphine (93.5 mg, 0.356 mmol), phthalimide (52.4 mg, 0.356 mmol) and diethylazodicarboxylate (62.1 mg, 0.356 mmol). This mixture was stirred at room temperature for 14 hours. The reaction mixture was concentrated and the resulting residue was purified by silica gel column chromatography (hexane:ethyl acetate=5:1) to obtain the title compound (81 mg, 65%).

Provenance & Evidence