2-Morpholinoethylamine → HCID 59553383, compound

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Reaction Steps

Compound is prepared from 3-fluoro-N-(4-{[2-(methylsulfonyl)pyrimidin-4-yl]oxy}-1-naphthyl)-5-morpholin-4-ylbenzamide and 2-morpholin-4-yl-ethylamine according to conditions described in general procedure C. Mp: 112-114° C.; 1H NMR (400 MHz, CDCl3) δ 2.33-2.43 (m, 6 H), 3.25-3.31 (m, 6 H), 3.65-3.71 (m, 4H), 3.84-3.89 (m, 4 H), 5.54 (s, 1 H), 6.08-6.10 (m, 1 H), 6.77-6.80 (m, 1 H), 7.09 (d, J=8.0 Hz, 1 H), 7.27-7.33 (m, 2 H), 7.50-7.57 (m, 2 H), 7.92-7.97 (m, 2 H), 8.13-8.17 (m, 2 H).

Provenance & Evidence