1-Ethylpiperazine → HCID 59553463, compound

Participants

Reaction Steps

Compound is prepared from 3-fluoro-N-(4-{[2-(methylsulfonyl)pyrimidin-4-yl]oxy}-1-naphthyl)-5-morpholin-4-ylbenzamide and N-ethylpiperazine according to conditions described in general procedure C. Mp: 185-186° C.; 1H NMR (400 MHz, DMSO-d6) δ 0.98 (t, J=6.9 Hz, 3 H), 2.31 (bs, 6 H), 3.27 (t, J=4.0 Hz, 6 H), 3.50 (bs, 2 H), 3.77 (t, J=4.4 Hz, 4 H), 6.22-6.24 (m, 1 H), 7.04 (d, J=12.0 Hz, 1 H), 7.27 (d, J=8.0 Hz, 1 H), 7.43 (d, J=8.0 Hz, 1 H), 7.50 (s, 1 H), 7.56-7.63 (m, 3 H), 7.84-7.86 (m, 1 H), 8.00 (d, J=8.0 Hz, 1 H), 8.27-8.29 (m, 1 H), 10.48 (s, 1 H).

Provenance & Evidence