Cyclohexylamine → HCID 59553235, compound

Participants

Reaction Steps

Compound is prepared from 3-fluoro-N-(4-{[2-(methylsulfonyl)pyrimidin-4-yl]oxy}-1-naphthyl)-5-morpholin-4-ylbenzamide and cyclohexylamine according to conditions described in general procedure C. Mp: 135-136° C.; 1H NMR (400 MHz, CDCl3) δ 1.10-1.25 (m, 6 H), 1.58-1.64 (m, 4 H), 1.19 (bs, 1 H), 3.27 (s, 4 H), 3.87-3.89 (m, 4 H), 4.90 (s, 1 H), 6.05 (s, 1 H), 6.78 (d, J=11.3 Hz, 1 H), 7.07 (d, J=7.8 Hz, 1 H), 7.26 (s, 1 H), 7.31-7.33 (m, 2 H), 7.51-7.61 (m, 2 H), 7.90 (d, J=8.6 Hz, 1 H), 7.97-8.00 (m, 2 H), 8.07 (s, 1 H), 8.12 (s, 1 H).

Provenance & Evidence