Cyclohexylamine → HCID 59553312, compound

Participants

Role	Name	HCID	Charge
Reactant	Cyclohexylamine	HCID 7965	—
Reactant	3-fluoro-N-[4-(2-methanesulfonyl-pyrimidin-4-yloxy)-naphthalen-1-yl]-5-piperidin-1-yl-benzamide	HCID 66737969	—
Product	HCID 59553312	HCID 59553312	—

Reaction Steps

Compound is prepared from 3-fluoro-N-[4-(2-methanesulfonyl-pyrimidin-4-yloxy)-naphthalen-1-yl]-5-piperidin-1-yl-benzamide and cyclohexylamine according to conditions described in general procedure C. Mp: 118-120° C.; 1H NMR (400 MHz, DMSO-d6) δ 1.00-1.23 (m, 6 H), 1.60-1.74 (m, 10 H), 3.10-3.29 (m, 5 H), 6.10-6.30 (m, 1 H), 6.97-7.00 (m, 2 H), 7.17 (d, J=8.8 Hz, 1 H), 7.40 (d, J=8.0 Hz, 1 H), 7.46 (s, 1 H), 7.55-7.62 (m, 3 H), 7.83 (d, J=8.0 Hz, 1 H), 7.99 (d, J=8.0 Hz, 1 H), 8.21 (s, 1 H), 10.47 (s, 1 H).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07829560B2
Source dataset	uspto-grants-2010_11
ORD ID	ord-6729608ab043482a86088c67d33cb71a
Source note	uspto-grants-2010_11