4-Methylpiperidine → HCID 59553372, compound

Participants

Role	Name	HCID	Charge
Reactant	4-Methylpiperidine	HCID 69381	—
Reactant	3-fluoro-N-[4-(2-methanesulfonyl-pyrimidin-4-yloxy)-naphthalen-1-yl]-5-piperidin-1-yl-benzamide	HCID 66737969	—
Product	HCID 59553372	HCID 59553372	—

Reaction Steps

Compound is prepared from 3-fluoro-N-[4-(2-methanesulfonyl-pyrimidin-4-yloxy)-naphthalen-1-yl]-5-piperidin-1-yl-benzamide and 4-methylpiperidine according to conditions described in general procedure C. Mp: 145-146° C.; 1H NMR (400 MHz, DMSO-d6) δ 0.86 (d, J=6.0 Hz, 3 H), 1.50-1.62 (m, 1 H), 3.30 (m, 8 H), 6.19-6.21 (m, 1 H), 6.99 (d, J=11.0 Hz, 1 H), 7.19 (d, J=9.0 Hz, 1 H), 7.41-7.43 (m, 1 H), 7.49 (s, 1N), 7.57-7.62 (m, 3 H), 7.85 (d, J=8.2 Hz, 1 H), 7.99 (d, J=8.5 Hz, 1 H), 8.25-8.27 (m, 1 H), 10.46 (s, 1 H).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07829560B2
Source dataset	uspto-grants-2010_11
ORD ID	ord-46d828f734604676ad63a392be118a4c
Source note	uspto-grants-2010_11