Cyanamide → HCID 59553320, compound

Participants

Reaction Steps

Compound is prepared from 3-fluoro-N-[4-(2-methanesulfonyl-pyrimidin-4-yloxy)-naphthalen-1-yl]-5-piperidin-1-yl-benzamide and cyanamide according to conditions described in general procedure C. Mp: 160-162° C.; 1H NMR (400 MHz, DMSO-d6) δ 1.58 (s, 6 H), 3.27-3.29 (m, 4 H), 6.32 (d, J=5.1 Hz, 1 H), 6.95 (d, J=12.4, 1 H), 7.15 (d, J=9.1 Hz, 1 H), 7.42-7.45 (m, 2 H), 7.55-7.62 (m, 3 H), 7.83 (d, J=8.8 Hz, 1 H), 7.97 (d, J=8.0 Hz, 1 H), 8.13 (d, J=5.8 Hz, 1 H), 10.44 (s, 1 H).

Provenance & Evidence