N-Methylisopropylamine → HCID 59553230, compound

Participants

Reaction Steps

Compound is prepared from 3-fluoro-N-[4-(2-methanesulfonyl-pyrimidin-4-yloxy)-naphthalen-1-yl]-5-piperidin-1-yl-benzamide and N-isopropylmethylamine according to conditions described in general procedure C. Mp: 102-104° C.; 1H NMR (400 MHz, DMSO-d6) δ 0.94 (bs, 6 H), 1.58 (s, 6 H), 2.70 (bs, 1 H), 3.26-3.31 (m, 7 H), 6.19 (d, J=6.0 Hz, 1 H), 6.96 (d, J=12.4 Hz, 1 H), 7.15 (d, J=8.8 Hz, 1 H), 7.40 (d, J=8.0 Hz, 1 H), 7.46 (s, 1 H), 7.51-7.62 (m, 3 H), 7.82 (d, J=7.6 Hz, 1 H), 7.97 (d, J=8.0 Hz, 1 H), 8.22-8.24 (m, 1 H), 10.43 (s, 1 H).

Provenance & Evidence