(2-Methoxyethyl)(methyl)amine → HCID 59553130, compound

Participants

Role	Name	HCID	Charge
Reactant	(2-Methoxyethyl)(methyl)amine	HCID 300977	—
Reactant	3-fluoro-N-[4-(2-methanesulfonyl-pyrimidin-4-yloxy)-naphthalen-1-yl]-5-piperidin-1-yl-benzamide	HCID 66737969	—
Product	HCID 59553130	HCID 59553130	—

Reaction Steps

Compound is prepared from 3-fluoro-N-[4-(2-methanesulfonyl-pyrimidin-4-yloxy)-naphthalen-1-yl]-5-piperidin-1-yl-benzamide and (2-methoxyethyl)methylamine according to conditions described in general procedure C. Mp: 81-82° C.; 1H NMR (400 MHz, CDCl3) δ 1.62-1.70 (m, 6 H), 3.06-3.40 (m, 14 H), 6.05 (s, 1 H), 6.76 (d, J=12.0 Hz, 1 H), 6.99 (d, J=7.8 Hz, 1 H), 7.26-7.30 (m, 2 H), 7.47-7.56 (m, 2 H), 7.88-7.96 (m, 3 H), 8.17 (s, 2 H).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07829560B2
Source dataset	uspto-grants-2010_11
ORD ID	ord-8b07568b9ccd4f0a98c2e558bc280b72
Source note	uspto-grants-2010_11