HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Tert-butoxy)benzoic acid → 3-tert-Butoxy-N-[4-(2-methylsulfanyl-pyrimidin-4-yloxy)-naphthalen-1-yl]-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Tert-butoxy)benzoic acid | HCID 586598 | — |
| Reactant | 4-(2-Methylsulfanylpyrimidin-4-yloxy)-naphthalen-1-ylamine | HCID 59553385 | — |
| Product | 3-tert-Butoxy-N-[4-(2-methylsulfanyl-pyrimidin-4-yloxy)-naphthalen-1-yl]-benzamide | HCID 59553200 | — |
Reaction Steps
Compound is prepared from 3-tert-butoxy-benzoic acid and 4-(2-methylsulfanyl-pyrimidin-4-yloxy)-naphthalen-1-ylamine according to conditions described in general procedure G. (0.130 g) (46%). Mp: 135-136° C. 1H NMR (300 MHz, DMSOd6) 10.49 (s, 1H), 8.56 (d, J=4.2 Hz, 1H), 8.04 (d, J=6.3 Hz, 1H), 7.83 (brd, 2H), 7.68-7.47 (m, 6H), 7.25 (d, J=5.7 Hz, 1H), 6.93 (d, J=4.5 Hz, 1H), 2.27 (s, 3H), 1.36 (s, 9H). MS: 460 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07829560B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-31cddc8641db44c5acf0c855d73d2848 |
| Source note | uspto-grants-2010_11 |