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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1171388Generated: November 1, 2026

3-(Trifluoromethyl)phenylboronic acid → HCID 59553267, compound

https://huagongshe.com/reaction/1171388

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Trifluoromethyl)phenylboronic acidHCID 2734388—
Reactant3-bromo-N-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-benzamideHCID 59553118—
ProductHCID 59553267HCID 59553267—

Reaction Steps

Compound is prepared from 3-bromo-N-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-benzamide and 3-trifluoromethylphenyl boronic acid according to conditions described in general procedure K. 1H NMR 300 MHz (DMSO-d6) δ 10.4 (s, 1H), 8.4 (s, 1H), 8.2 (m, 1H), 8.05 (s, 2H), 8.03 (d, 1H), 8.0 (d, 1H), 7.9 (m, 1H), 7.4-7.75 (m, 6H), 7.0 (d, 1H), 4.3 (t, 2H), 3.6 (m, 4H), 2.9 (t, 2H), 2.55 (m, 4H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07829560B2
Source datasetuspto-grants-2010_11
ORD IDord-1810aca85c2f4dd2ba3bfd2464f911b9
Source noteuspto-grants-2010_11