HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisobutylaluminum hydride → 4-Iodo-2-propoxybenzenemethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisobutylaluminum hydride | HCID 14487 | — |
| Reactant | HCID 68769381 | HCID 68769381 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 4-Iodo-2-propoxybenzenemethanol | HCID 68768450 | — |
Reaction Steps
The procedure is the same as that described above, using 14 g of methyl 4-iodo-2-propoxybenzoate, 450 ml of toluene and 87.5 ml of DiBAlH. The product is purified by chromatography on a silica column, eluted with a heptane/ethyl acetate 9:1 mixture. After evaporation of the solvents, 11.3 g (88%) of the expected compound are recovered in the form of a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07829588B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-363731b29f9f4cd48a499b819f310336 |
| Source note | uspto-grants-2010_11 |