Dimethyl Sulfoxide → 2-[4-chloro-2-fluoro-5-(2-pyrimidyloxy)phenyl]hexahydro-3-thioxo-1H-[1,2,4]triazolo[1,2-a]pyridazin-1-one
Reaction equation
[C:28](=[O:29])([O-:30])[O-:31].[CH3:34][S:35]([CH3:36])=[O:37].[Cl:1][c:2]1[cH:3][c:4]([F:20])[c:5](-[n:9]2[c:10](=[S:19])[n:11]3[n:12]([c:17]2=[O:18])[CH2:13][CH2:14][CH2:15][CH2:16]3)[cH:6][c:7]1[OH:8].[Cl:21][c:22]1[n:23][cH:24][cH:25][cH:26][n:27]1.[K+:32].[K+:33]>>[Cl:1][c:2]1[cH:3][c:4]([F:20])[c:5](-[n:9]2[c:10](=[S:19])[n:11]3[n:12]([c:17]2=[O:18])[CH2:13][CH2:14][CH2:15][CH2:16]3)[cH:6][c:7]1[O:8][c:22]1[n:23][cH:24][cH:25][cH:26][n:27]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-c1ce048b4d24461094534af9842c22b0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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