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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1171778Generated: October 27, 2026

Ethyl 3-amino-1H-pyrrole-2-carboxylate → 3-({[3-(2-Ethoxyethoxy)pyridin-2-yl]methyl}amino)-1H-pyrrole-2-carboxylic acid ethyl ester

https://huagongshe.com/reaction/1171778

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 3-amino-1H-pyrrole-2-carboxylateHCID 2773439—
Reactant3-(2-Ethoxyethoxy)pyridine-2-carbaldehydeHCID 86623129—
Product3-({[3-(2-Ethoxyethoxy)pyridin-2-yl]methyl}amino)-1H-pyrrole-2-carboxylic acid ethyl esterHCID 6706848273%

Reaction Steps

The title compound (0.17 g, 73%) was prepared in accordance with general method A using 3-(2-ethoxyethoxy)pyridine-2-carbaldehyde (0.21 g, 1.08 mmol) and 3-amino-1H-pyrrole-2-carboxylic acid ethyl ester (0.11 g, 0.717 mmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07829707B2
Source datasetuspto-grants-2010_11
ORD IDord-e30fcf606be94460b34c355986d2ef59
Source noteuspto-grants-2010_11