HCID 86649831, compound → HCID 66854497, compound

HRID 1171808Notes

Reaction equation

HRID 1171808 reaction equation
[O:1]=[C:2]1[CH2:19][CH2:18][C@@:17]2([CH3:20])[C:4]([CH2:5][CH2:6][C@@H:7]3[C@@H:16]2[CH2:15][CH2:14][C@@:12]2([CH3:13])[C@H:8]3[CH2:9][CH2:10][CH:11]2[C:21]([NH:23][CH2:24][CH2:25][NH:26]C(=O)OC(C)(C)C)=[O:22])=[CH:3]1>O>[NH2:26][CH2:25][CH2:24][NH:23][C:21]([CH:11]1[CH2:10][CH2:9][C@H:8]2[C@H:7]3[C@H:16]([CH2:15][CH2:14][C@:12]12[CH3:13])[C@:17]1([CH3:20])[C:4](=[CH:3][C:2](=[O:1])[CH2:19][CH2:18]1)[CH2:5][CH2:6]3)=[O:22]

Participants

3

Reactant 1

HCID 86649831HCID 86649831, compound

Product 1

HCID 66854497HCID 66854497, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To 16.5 mg of Tert-Butyl 2-{[(3-oxoandrost-4-en-17-yl)carbonyl]amino}-ethylcarbamate was added 0.5 ml of 95% trifluoroacacetic acid/water. On standing for 2 hours the volatile components were removed using a rotary evaporator. The resulting product (Formula XIV), which was an oil, was used without further purification. Mass spectrum: 359.23 (M+H)

Workup

  1. customthe volatile components were removed
  2. customa rotary evaporator
  3. customwas used without further purification

Sources & evidence

ORD record
ord-1f78ce12e3b74167a66d29661519cab4
Source dataset
uspto-grants-2010_11
Patent number
US07829714B2

Reaction notes

Loading…