7-Chloro-8-(4-chlorophenyl)-2-(6-(trifluoromethyl)pyridin-3-yl)methyl-[1,2,4]triazolo[4,3-b]pyridazin-3(2H)-one → 8-(4-chlorophenyl)-7-(4-(oxazol-2-yl)phenyl)-2-((6-(trifluoromethyl)pyridin-3-yl)methyl)-[1,2,4]triazolo[4,3-b]pyridazin-3(2H)-one

HRID 117208Notes

Reaction equation

HRID 117208 reaction equation
[CH3:30][C:31]1([CH3:32])[C:33]([CH3:34])([CH3:35])[O:36][B:37]([c:38]2[cH:39][cH:40][c:41](-[c:44]3[o:45][cH:46][cH:47][n:48]3)[cH:42][cH:43]2)[O:49]1.[Cl:1][c:2]1[c:3](-[c:23]2[cH:24][cH:25][c:26]([Cl:29])[cH:27][cH:28]2)[c:4]2[n:5]([n:6][cH:7]1)[c:8](=[O:22])[n:9]([CH2:11][c:12]1[cH:13][n:14][c:15]([C:18]([F:19])([F:20])[F:21])[cH:16][cH:17]1)[n:10]2>>[c:2]1(-[c:38]2[cH:39][cH:40][c:41](-[c:44]3[o:45][cH:46][cH:47][n:48]3)[cH:42][cH:43]2)[c:3](-[c:23]2[cH:24][cH:25][c:26]([Cl:29])[cH:27][cH:28]2)[c:4]2[n:5]([n:6][cH:7]1)[c:8](=[O:22])[n:9]([CH2:11][c:12]1[cH:13][n:14][c:15]([C:18]([F:19])([F:20])[F:21])[cH:16][cH:17]1)[n:10]2

Participants

3

Reactant 2

HCID 597169037-Chloro-8-(4-chlorophenyl)-2-(6-(trifluoromethyl)pyridin-3-yl)methyl-[1,2,4]triazolo[4,3-b]pyridazin-3(2H)-oneHCID 597169152-(4-(Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-1,3-oxazole

Product 1

HCID 597165758-(4-chlorophenyl)-7-(4-(oxazol-2-yl)phenyl)-2-((6-(trifluoromethyl)pyridin-3-yl)methyl)-[1,2,4]triazolo[4,3-b]pyridazin-3(2H)-one

Sources & evidence

ORD record
ord-a7e2dbc2ec384fd38926ab65561a55ef
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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