HCID 68772019, compound → HCID 11536065, compound

Participants

Reaction Steps

To a solution of Example 2B (100 mg, 0.041 mmol) in 1:1 in methanol (2 mL), two drops of concentrated HCl and 10% palladium on carbon (10 mg) were added. The solution was purged with nitrogen and subjected to an atmosphere of H2 over a twelve hour period. The solution was filtered through Celite and concentrated to give the title compound. 1H NMR (300 MHz, C5D5N) δ ppm 7.26 (s, 1H), 7.17-7.19 (m, 2H), 3.96-3.99 (m, 1H), 3.65-3.69 (m, 1H), 2.94-2.96 (m, 1H), 2.06-2.08 (m, 1H), 1.80-1.83 (m, 1H), 1.58-1.67 (m, 2H), 1.25-1.39 (m, 3H). MS (ESI+) m/z 245 (M+H)+.

Provenance & Evidence