Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Thionyl Chloride → 4-Fluoro-N-methyl-benzimidoyl chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | 4-fluoro-N-methylbenzamide | HCID 4074247 | — |
| 생성물 | 4-Fluoro-N-methyl-benzimidoyl chloride | HCID 86615130 | — |
반응 단계
A suspension of 4-fluoro-N-methyl-benzamide (CAS: 701-49-5, 0.106 g, 0.69 mmol) in thionyl chloride (202 mL, 2.78 mmol) was refluxed for 1 h 30 min. The solvent was removed under reduced pressure, then toluene was added and the solvent was evaporated under reduced pressure to afford a yellow oil used immediately for the next step.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07834035B2 |
| 출처 데이터셋 | uspto-grants-2010_11 |
| ORD ID | ord-cb76aba1c7d0460b9ef34c45e6f90953 |
| 출처 메모 | uspto-grants-2010_11 |