1-[4-(4-Chlorophenoxy)-2-propylphenyl]-2-(4-methoxyphenoxy)ethanone → 3-[4-(4-Chlorophenoxy)-2-propylphenyl]-5-methoxy-1-benzofuran

Participants

Reaction Conditions

Reaction Steps

A mixture of the product from Step 9 (0.46 g, 1.1 mmol) and Amberlyst-15 (0.50 g) in xylene (10 mL) was heated at 140° C. for 2 h. The reaction mixture was filtered and the filtrate was concentrated. The residue was purified by chromatography on silica gel to give the title product.

Provenance & Evidence