(+)-Methyl lactate → HCID 11846567, compound

HRID 1172821Notes

Reaction equation

HRID 1172821 reaction equation
[Cl:1][C:2]1[CH:27]=[CH:26][C:5]([O:6][C:7]2[CH:12]=[CH:11][C:10]([C:13]3[C:17]4[CH:18]=[C:19]([OH:22])[CH:20]=[CH:21][C:16]=4[O:15][N:14]=3)=[C:9]([CH2:23][CH2:24][CH3:25])[CH:8]=2)=[CH:4][CH:3]=1.[C:28]([O:33]C)(=[O:32])[C@@H:29]([CH3:31])O>>[Cl:1][C:2]1[CH:27]=[CH:26][C:5]([O:6][C:7]2[CH:12]=[CH:11][C:10]([C:13]3[C:17]4[CH:18]=[C:19]([O:22][C@@H:29]([CH3:31])[C:28]([OH:33])=[O:32])[CH:20]=[CH:21][C:16]=4[O:15][N:14]=3)=[C:9]([CH2:23][CH2:24][CH3:25])[CH:8]=2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 637514(+)-Methyl lactateHCID 68691874HCID 68691874, compound

Product 1

HCID 11846567HCID 11846567, compound

Procedure

The phenol from Step 6 (0.38 g, 1.0 mmol) and methyl (R)-lactate (0.16 g, 1.5 mmol) was reacted according the general procedure described in Step 11 of Example 1 to give the title compound as a white solid.

Sources & evidence

ORD record
ord-4b66e9dd189a4c92a23ae664d6af44ac
Source dataset
uspto-grants-2010_11
Patent number
US07834036B2

Reaction notes

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