(+)-Methyl lactate → HCID 11846739, compound

HRID 1172823Notes

Reaction equation

HRID 1172823 reaction equation
[Cl:1][C:2]1[C:7]2[C:8]([C:11]3[CH:16]=[CH:15][C:14]([O:17][C:18]4[CH:23]=[CH:22][C:21]([Cl:24])=[CH:20][CH:19]=4)=[CH:13][C:12]=3[CH2:25][CH2:26][CH3:27])=[N:9][O:10][C:6]=2[CH:5]=[CH:4][C:3]=1[OH:28].[C:29]([O:34]C)(=[O:33])[C@@H:30]([CH3:32])O>>[Cl:1][C:2]1[C:7]2[C:8]([C:11]3[CH:16]=[CH:15][C:14]([O:17][C:18]4[CH:23]=[CH:22][C:21]([Cl:24])=[CH:20][CH:19]=4)=[CH:13][C:12]=3[CH2:25][CH2:26][CH3:27])=[N:9][O:10][C:6]=2[CH:5]=[CH:4][C:3]=1[O:28][C@@H:30]([CH3:32])[C:29]([OH:34])=[O:33]

Participants

3

Reactant 2

HCID 637514(+)-Methyl lactateHCID 68698119HCID 68698119, compound

Product 1

HCID 11846739HCID 11846739, compound

Procedure

The phenol product from Step 1 (0.38 g, 0.9 mmol) and methyl (R)-lactate (0.16 g, 1.5 mmol) was reacted according the general procedure described in Step 11 of Example 1 to give the title compound as a white solid.

Sources & evidence

ORD record
ord-e9baed130c0c49209c890aca8a8a7b00
Source dataset
uspto-grants-2010_11
Patent number
US07834036B2

Reaction notes

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