HuagongsheHuagongshe Chemistry Print Report · For research reference only
methyl (S)-lactate → (2R)-2-({6-chloro-3-[4-(4-chlorophenoxy)-2-propylphenyl]-1,2-benzisoxazol-5-yl}oxy)propanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | methyl (S)-lactate | HCID 94386 | — |
| Reactant | 6-Chloro-3-[4-(4-chlorophenoxy)-2-propylphenyl]-1,2-benzisoxazol-5-ol | HCID 68691100 | — |
| Product | (2R)-2-({6-chloro-3-[4-(4-chlorophenoxy)-2-propylphenyl]-1,2-benzisoxazol-5-yl}oxy)propanoic acid | HCID 25121897 | — |
Reaction Steps
The phenol from Step 6 (0.38 g, 1.0 mmol) and methyl (S)-lactate (0.16 g, 1.5 mmol) was reacted according the general procedure described in Step 11 of Example 1 to give the title compound as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07834036B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-a278314071d74c468c384612fe620e79 |
| Source note | uspto-grants-2010_11 |