HCID 68694432, compound → HCID 68695399, compound

Participants

Reaction Conditions

Reaction Steps

The product from Step 9 (4.3 g, 10 mmol) and boron tribromide dimethyl sulfide complex (12.4 g, 40 mmol) were mixed in dichloroethane (100 mL). The resulting solution was heated at 85° C. for 18 h. The mixture was diluted with ethyl acetate (200 mL), washed with a saturated solution of sodium bicarbonate, dried over magnesium sulfate and concentrated. The residue was purified by chromatography on silica gel to give the title product as a white solid.

Provenance & Evidence