(+)-Methyl lactate → HCID 11847059, compound

HRID 1172843Notes

Reaction equation

HRID 1172843 reaction equation
[Cl:1][C:2]1[CH:10]=[C:9]2[C:5]([C:6]([C:12]3[C:13]([CH2:26][CH2:27][CH3:28])=[N:14][C:15]([O:18][C:19]4[CH:24]=[CH:23][C:22]([Cl:25])=[CH:21][CH:20]=4)=[CH:16][CH:17]=3)=[N:7][N:8]2[CH3:11])=[CH:4][C:3]=1[OH:29].[C:30]([O:35]C)(=[O:34])[C@@H:31]([CH3:33])O>>[Cl:1][C:2]1[CH:10]=[C:9]2[C:5]([C:6]([C:12]3[C:13]([CH2:26][CH2:27][CH3:28])=[N:14][C:15]([O:18][C:19]4[CH:24]=[CH:23][C:22]([Cl:25])=[CH:21][CH:20]=4)=[CH:16][CH:17]=3)=[N:7][N:8]2[CH3:11])=[CH:4][C:3]=1[O:29][C@@H:31]([CH3:33])[C:30]([OH:35])=[O:34]

Participants

3

Reactant 2

HCID 637514(+)-Methyl lactateHCID 68691967HCID 68691967, compound

Product 1

HCID 11847059HCID 11847059, compound

Procedure

The phenol from Step 2 (0.43 g, 1.0 mmol) and methyl (R)-lactate (0.16 g, 1.5 mmol) were reacted according the general procedure described in Step 11 of Example 1 to give the title compound as a white solid.

Sources & evidence

ORD record
ord-42426a065c394db78cbf142325b90cb7
Source dataset
uspto-grants-2010_11
Patent number
US07834036B2

Reaction notes

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