Hydroxylamine → HCID 59556753, compound

Participants

Reaction Conditions

Reaction Steps

3-bromo-4-isopropoxybenzonitrile (0.68 g, 2.83 mmol) and hydroxylamine (0.208 ml, 3.12 mmol) were combined in EtOH (20 ml). The reaction mixture was heated at 65° C. for 16 hr. The reaction mixture was concentrated to afford (Z)-3-bromo-N′-hydroxy-4-isopropoxybenzimidamide (0.76 g, 2.78 mmol, 98% yield) as pale yellow solid. LC/MS (Table 1, Method a) Rt=2.89 min.; MS m/z: 275.00 (M+H)+.

Provenance & Evidence