HuagongsheHuagongshe Chemistry Print Report · For research reference only
1H-imidazole-2-carbaldehyde → 1-(1H-Imidazol-2-ylmethyl)-5-phenoxy-1,2,3,4-tetrahydro-quinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1H-imidazole-2-carbaldehyde | HCID 24955 | — |
| Reactant | 5-Phenoxy-1,2,3,4-tetrahydroquinoline | HCID 487547 | — |
| Reactant | Sodium cyanoborohydride | HCID 5003444 | — |
| Catalyst | Zincchloride | HCID 3007855 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 1-(1H-Imidazol-2-ylmethyl)-5-phenoxy-1,2,3,4-tetrahydro-quinoline | HCID 24786231 | — |
Reaction Steps
Prepared analogously to Example 1, from 5-phenoxy-1,2,3,4-tetrahydro-quinoline, imidazole-2-carboxaldehyde, zinc chloride and sodium cyanoborohydride in methanol. MS (ISP): 306.3 ([M+H]+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07834044B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-a086ec077fea473b88ffcff308ab65b2 |
| Source note | uspto-grants-2010_11 |