Imidazole → HCID 22228535, compound

Participants

Reaction Conditions

Reaction Steps

To 4-(3-bromopropyl)-N-(3-chloro-1H-indole-7-yl)benzenesulfonamide (213 mg, 0.5 mmol) were added 170 mg (2.5 mmol) of imidazole and 6 ml of dimethylformamide, followed by heating at 80° C. for 3 hours in a nitrogen atmosphere. Then, the reaction mixture was poured into water and extracted with chloroform. The extract was dried over magnesium sulfate and concentrated. Then, the residue was purified by silica gel column chromatography, to give 160 mg of the title compound.

Provenance & Evidence