Imidazole → HCID 22228569, compound

Participants

Reaction Conditions

Reaction Steps

557 mg (1.13 mmol) of 4-[N-(2-bromoethyl)sulfamoyl]-N-(3-chloro-1H-indole-7-yl)benzenesulfonamide and 820 mg (12.0 mmol) of imidazole were added to 10 ml of dimethylformamide and the mixture was stirred at 80° C. for 2 days. After concentrating, the residue was dissolved in ethyl acetate. The mixture was washed with water, dried over sodium sulfate and concentrated. The residue was purified by silica gel column chromatography, to give 324 mg of the title compound.

Provenance & Evidence