反应详情

N-Acetyl-N-(3-aminophenethyl)amine (1.7 g, Production Example 29b) was dissolved in pyridine (5 ml). Under ice-cooling, ethyl chloroformate (1.4 ml) was added dropwise thereinto, followed by stirring at room temperature for one hour. Then, the mixture was ice-cooled again and water was added thereto. The mixture was extracted with ethyl acetate, and the extract was washed with brine and dried over anhydrous magnesium sulfate. The solvent was evaporated, to give the title compound (2.358 g, 97%) as a yellow oil.

1. temperatureUnder ice-cooling
2. temperaturecooled again
3. extractionThe mixture was extracted with ethyl acetate
4. washthe extract was washed with brine
5. dry with materialdried over anhydrous magnesium sulfate
6. customThe solvent was evaporated