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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1173213Generated: October 30, 2026

4-(1-Hydroxy-4-oxocyclohexyl)benzonitrile → 6-(1-Hydroxy-4-oxocyclohexyl)nicotinonitrile

https://huagongshe.com/reaction/1173213

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(1-Hydroxy-4-oxocyclohexyl)benzonitrileHCID 66787229—
Reactant6-(8-Hydroxy-1,4-dioxaspiro[4.5]dec-8-yl)nicotinonitrileHCID 66787727—
Product6-(1-Hydroxy-4-oxocyclohexyl)nicotinonitrileHCID 66788003—

Reaction Steps

The title compound was synthesized from 6-(8-hydroxy-1,4-dioxaspiro[4.5]dec-8-yl)nicotinonitrile using the sane typical deprotection procedure as for 4-(1-hydroxy-4-oxocyclohexyl)benzonitrile.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07834021B2
Source datasetuspto-grants-2010_11
ORD IDord-4c61d3ba0b1b410a832c272543ff0f6a
Source noteuspto-grants-2010_11